New Chemical Entities with improved safety, efficacy, dosing, and convenience

Development Pipeline

Programs

Description

PRE-CLINICAL

IND ENABLING

PHASE 1

Phase 2

PHASE 3

GM-2505: Short-Acting
5-HT2AR Agonist

2 hour treatment duration
Indications: Depression
Non-hallucinogenic neuroplastogen
Indications: Depression, Anxiety
Improved Cardiac Safety Profile, Improved Efficacy
Indications: Opioid Use Disorder, PTSD, TBI
Orally Bioavailable, Rapid-acting, Non Dissociative, Potential At-Home Use
Indications: Depression
Neuroplastogens
GM-1020: NMDAR Antagonist
GM-3009: Safer Ibogaine Analog

Program

GM-1020: Oral NMDAR Antagonist

Description

Orally Bioavailable, Rapid-acting, Non Dissociative, Potential At-Home Use
Indications: Depression, Bipolar Depression and Others

Phase

Phase 2
Pre-Clinical|IND| Phase 1Phase 2

Program

GM-2505: Short Acting 5-HT2A Agonist

Description

60-90 minute duration
Indications: Depression, Anxiety and Others

Phase

Phase 2
Pre-Clinical|IND| Phase 1Phase 2

Program

GM-5022: Oral Neuroplastogen

Description

Non-hallucinogenic neuroplastogen
Indications: Depression, Anxiety and Others

Phase

IND Enabling
Discovery | Pre-Clinical | IND Phase 1

Program

GM-3009: Safer Ibogaine Analogs

Description

Improved Cardiac Safety Profile, Improved Efficacy
Indications: Opioid Use Disorder, PTSD, TBI

Phase

Pre-clinical
Discovery | Pre-Clinical | IND Phase 1
Gilgamesh Pharmaceuticals
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info@gilgameshpharmaceutical.com
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